Search on: FOCAL ADHESIONS 
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Descriptor English:   Focal Adhesions 
Descriptor Spanish:   Adhesiones Focales 
Descriptor Portuguese:   Aderências Focais 
Synonyms English:   Adhesion Plaques
Cell-Matrix Adherens Junctions
Focal Contacts  
Tree Number:   A11.284.149.165.165.285
Definition English:   An anchoring junction of the cell to a non-cellular substrate. It is composed of a specialized area of the plasma membrane where bundles of MICROFILAMENTS terminate and attach to the transmembrane linkers, INTEGRINS, which in turn attach through their extracellular domains to EXTRACELLULAR MATRIX PROTEINS. 
See Related English:   Cell Adhesion
 
History Note English:   2001 
Allowable Qualifiers English:  
chemistry classification
drug effects enzymology
genetics immunology
metabolism microbiology
pathology physiology
parasitology radiography
radiation effects radionuclide imaging
secretion transplantation
ultrastructure ultrasonography
virology  
Record Number:   35265 
Unique Identifier:   D022001 

Occurrence in VHL:
 

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